MS- 2-10
Mini-symposium title
2-10 – Biotribology and Interface Mechanics of Tissue and Devices
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Organisers
Rosaire Mongrain (McGill University), Mark Driscoll (McGill University)
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Mini-symposium description
This mini-symposium aims at establishing a better understanding of biotribology and interface mechanics with the interaction of medical technologies and tissue. Biotribology includes concepts of friction, wear, and lubrication of interacting surfaces when surfaces are in sliding contact. It plays a key role in cardiovascular applications (catheter navigation, endovascular technology deployment, coatings and surface treatment), musculoskeletal (synovial joints, prosthetics wear, tissue repair), during fusion or bone consolidation in orthopeadics, and oncology (cells adhesion, liquid biopsy, infusion therapies). Interface mechanics includes contact and shear forces between the soft biological tissue and devices and transport phenomena (diffusion of molecules, particles convection). Interestingly, these surface characteristics are not yet incorporated in the design of medical technologies for optimal operation for minimizing discomfort and pain, tissue damage (desquamation, perforation) and therapeutic efficiency (positioning, delivery).
Specific attention is placed on modeling methods (theoretical, numerical, experimental) for investigating dynamic friction, contact forces, lubrication, wear, tissue damage, short- and long-term structural integrity, surface functionalization, patterning and coatings for enhancing bio-integration and therapeutic goals.
The particular topics to be covered in this mini-symposium, but not limited to, include:
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Surface structure (texture, roughness) characterization (SEM, profilometry)
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Surface properties characterization (micro/nano indentation, AFM, scratch tests)
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Contact forces models (hard and soft materials)
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Friction models for tissue-device interaction (theoretical, numerical, experimental)
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Film, hydrodynamic suspension and instabilities effects
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Diffusion of molecules and particles transport
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Catheter navigation
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Endovascular technology deployment (stent, graft, valves)
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Surgical tools–tissue interaction (vascular, musculoskeletal, eye, pleurae, skin, oral cavity)
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Liquid and solid biopsy procedures
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Prostheses and implants operation and longevity (wear, degradation).
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